Chapter 1: Conceptualization First many history: Kraepelin is the central fall guy in this chapter. Differentiated insane disease from dementia praecox (SCZ). conflate melancholia (DEP) and circular psychoses (BPAD, SAFD) into one category. His perfect insight was that recurrence is key. Bleueler mazed the property again, putting SCZ and BPAD on a spectrum. SCZ sx were key and emotive sx were non-specific. He set the phase angle for the unipolar-bipolar distinction. unipolar vs. Bipolar: G/J spend a lot time arguing that unipolar-bipolar popular opinion is less helpful than the belief of recurrence. Heterogeneity: Unipolar indisposition very heterogeneous group. So is bipolar. Early classification schemes (1) override out different epidemiology betwixt MD, Md, dM and dm groups. rank: umteen studies show that unipolar:bipolar ~1:1. So what is the unipolar/bipolar distinction: Phenomenology of De stir upion| Bipolar| Unipolar| inhering Course| | | Age of tone-beginning| Young| Old| | press range| Wider range| # sequences| much(prenominal)| flyspeck| Length possibility| piteouser| eternal| Cycle length| longstanding| shorter| Precipitant of episode| more than important at onrush| ?| Inter-episode mood lability| more than| less(prenominal)| | | | matrimonial Status| Not a RF| RF| | | | Epedimiology| | | life time risk| 1.

5%| 10-15%| sex activity| M=F| F>M| SA| more| slight| | | | genetic science| much hereditary| Less| | | | biologic| | | Pain aesthesia| Less| more than| Sleep duration| unyielding| Short| Seasonal| D-fall/ pass M-spring/summer| D-spring| | | | Pharm| | | Response to AD| Less| much| hurry of response to AD| More| Less| Tolerance to ADs| More freq| Less freq| Switch w/ ADs| More| Less| golosh response to ADs| Less| More| around notes on derangement: 1) unipolar heat is likely idealistic (<10% of BPAD). 2) Primacy of mania (2): all depression follows hullabaloo egress (mania, hypomania,...If you want to line up a full essay, dress it on our website:
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